Antimicrobial effect of ozonated water on bacteria invading dentinal tubules

被引:141
作者
Nagayoshi, M
Kitamura, C
Fukuizumi, T
Nishihara, T
Terashita, M
机构
[1] Kyushu Dent Coll, Dept Operat Dent & Endodont, Kokurakita Ku, Kitakyushu, Fukuoka 8038580, Japan
[2] Kyushu Dent Coll, Dept Oral Microbiol, Kitakyushu, Fukuoka, Japan
关键词
D O I
10.1097/00004770-200411000-00007
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Ozone is known to act as a strong antimicrobial agent against bacteria, fungi, and viruses. In the present study, we examined the effect of ozonated water against Enterococcus faecalis and Streptcoccus mutans infections in vitro in bovine dentin. After irrigation with ozonated water, the viability of E faecalis and S. mutans invading dentinal tubules significantly decreased. Notably, when the specimen was irrigated with sonication, ozonated water had nearly the same antimicrobial activity as 2.5% sodium hypochlorite (NaOCl). We also compared the cytotoxicity against L-929 mouse fibroblasts between ozonated water and NaOCl. The metabolic activity of fibroblasts was high when the cells were treated with ozonated water, whereas that of fibroblasts significantly decreased when the cells were treated with 2.5% NaOCl. These results suggest that ozonated water application may be useful for endodontic therapy.
引用
收藏
页码:778 / 781
页数:4
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