Effects of gemfibrozil conversion to fenofibrate on lipids in patients on statin therapy

被引:6
作者
Corbelli, JC
Bullano, MF
Willey, VJ
Cziraky, MJ
Corbelli, ME
Waugh, W
机构
[1] Buffalo Cardiol & Pulm Associates, Williamsville, NY 14231 USA
[2] Hlth Core Inc, Newark, DE USA
[3] WellPoint Pharm Management, Canoga Pk, CA USA
关键词
D O I
10.1016/S0002-9149(02)02880-1
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Patients stabilized on statin therapy who were switched from gemfibrozil to fenotibrate due to inadequate lipid response or adverse effects experienced significant improvements in total cholesterol, triglycerides, high-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol levels, with no significant change in low-density lipoprotein cholesterol. Patients did not have any clinically significant elevations in liver function tests or creatine phosphokinase levels while on either-fibrate in combination with a statin.
引用
收藏
页码:1388 / +
页数:5
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