An amidyl radical cyclisation approach towards the synthesis of β-lactams

被引:28
作者
Clark, AJ [1 ]
Peacock, JL [1 ]
机构
[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England
关键词
D O I
10.1016/S0040-4039(97)10772-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Amidyl radicals generated from tributylstannane mediated homolysis of O-benzoyl hydroxamic acid derivatives (2a-d) undergo 4-exo trig cyclisation to furnish beta-lactam derivatives (4a-d). (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码:1265 / 1268
页数:4
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