A rationally designed macrocyclic cavitand that kills bacteria with high efficacy and good selectivity

被引：29

作者：

Choi, Jinny

Kim, Jeeyeon

Kim, Kimoon ^{[1
]}

Yang, Sung-Tae

Kim, Jae-Il

Jon, Sangyong

机构：

[1] Pohang Univ Sci & Technol, Natl Creat Res Initiat, Ctr Smart Supramol, Pohang 790784, South Korea

[2] Pohang Univ Sci & Technol, Dept Chem, Pohang 790784, South Korea

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 11期

关键词：

D O I：

10.1039/b617005f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An amphiphilic macrocyclic cavitand that shows good antibacterial activity, comparable to that of peptide-based antibiotics was developed by rational design and its antibacterial selectivity over mammalian cells was examined.

引用

页码：1151 / 1153

页数：3

共 19 条

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