Correlated neuronal discharges that increase coding efficiency during perceptual discrimination

被引:168
作者
Romo, R [1 ]
Hernández, A
Zainos, A
Salinas, E
机构
[1] Univ Nacl Autonoma Mexico, Inst Fisiol Celular, Mexico City 04510, DF, Mexico
[2] Wake Forest Univ, Bowman Gray Sch Med, Dept Neurobiol & Anat, Winston Salem, NC 27157 USA
关键词
D O I
10.1016/S0896-6273(03)00287-3
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
During a sensory discrimination task, the responses of multiple sensory neurons must be combined to generate a choice. The optimal combination of responses is determined both by their dependence on the sensory stimulus and by their cofluctuations across trials-that is, the noise correlations. Positively correlated noise is considered deleterious, because it limits the coding accuracy of populations of similarly tuned neurons. However, positively correlated fluctuations between differently tuned neurons actually increase coding accuracy, because they allow the common noise to be subtracted without signal loss. This is demonstrated with data recorded from the secondary somatosensory cortex of monkeys performing a vibrotactile discrimination task. The results indicate that positive correlations are not always harmful and may be exploited by cortical networks to enhance the neural representation of features to be discriminated.
引用
收藏
页码:649 / 657
页数:9
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