Lack of serological evidence for an association between simian virus 40 and lymphoma

被引：61

作者：

de Sanjose, S

Shah, KV

Domingo-Domenech, E

Engels, EA

de Sevilla, AF

Alvaro, T

Garcia-Villanueva, M

Romagosa, V

Gonzalez-Barca, E

Viscidi, RP

机构：

[1] NCI, Viral Epidemiol Branch, Rockville, MD 20852 USA

[2] Inst Catala Oncol, Barcelona, Spain

[3] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD 21218 USA

[4] Hosp Verge Cinta, Tortosa, Spain

[5] Ramon & Cajal, Madrid, Spain

[6] Ciutat Sanitaria & Univ Bellvitge, Barcelona, Spain

[7] Johns Hopkins Univ, Sch Med, Dept Pediat, Stanley Div Dev Neurovirol, Baltimore, MD 21205 USA

来源：

INTERNATIONAL JOURNAL OF CANCER | 2003年 / 104卷 / 04期

关键词：

D O I：

10.1002/ijc.10993

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Recent studies have implicated simian virus 40 (SV40) in non-Hodgkin's lymphomas based on detection of SV40 DNA sequences. We employed a virus-like-particle (VLP)-based enzyme immunoassay for antibodies to SV40 to test sera from 520 lymphoma cases and 587 controls in Spain. The SV40 seroprevalence was 9.5% in controls and 5.9% in cases. Antibody levels of the positive sera were low. There was no association of SV40 seropositivity with any subtype of lymphoma. VLPs of the human BK virus substantially inhibited the SV40 reactivity of human sera. There was no serological evidence of widespread SV40 infection and no association of SV40 seropositivity with human lymphomas in Spain. (C) 2003 Wiley-Liss, Inc.

引用

页码：522 / 524

页数：3

共 7 条

[1] Simian virus 40 infection in lymphoproliferative disorders [J].

Capello, D ;

Rossi, D ;

Gaudino, G ;

Carbone, A ;

Gaidano, G .

LANCET, 2003, 361 (9351) :88-89

[2]

Perez Gallardo F, 1965, Rev Sanid Hig Publica (Madr), V39, P537

[3]

Shah KV, 2000, REV MED VIROL, V10, P31, DOI 10.1002/(SICI)1099-1654(200001/02)10:1<31::AID-RMV260>3.0.CO

[4]

2-I

[5] Presence of simian virus 40 DNA sequences in human lymphomas [J].

Shivapurkar, N ;

Harada, K ;

Reddy, J ;

Scheuermann, RH ;

Xu, Y ;

McKenna, RW ;

Milchgrub, S ;

Kroft, SH ;

Feng, ZD ;

Gazdar, AF .

LANCET, 2002, 359 (9309) :851-852

[6] Association between simian virus 40 and non-Hodgkin lymphoma [J].

Vilchez, RA ;

Madden, CR ;

Kozinetz, CA ;

Halvorson, SJ ;

White, ZS ;

Jorgensen, JL ;

Finch, CJ ;

Butel, JS .

LANCET, 2002, 359 (9309) :817-823

[7]

VISERDI RP, 2003, IN PRESS CLIN DIAG I, V10

← 1 →