Gold Nanocages as Photothermal Transducers for Cancer Treatment

被引：607

作者：

Chen, Jingyi ^{[1
]}

Glaus, Charles ^{[2
]}

Laforest, Richard ^{[2
]}

Zhang, Qiang ^{[1
]}

Yang, Miaoxian ^{[1
]}

Gidding, Michael ^{[3
]}

Welch, Michael J. ^{[2
]}

Xia, Younan ^{[1
]}

机构：

[1] Washington Univ, Dept Biomed Engn, St Louis, MO 63130 USA

[2] Washington Univ, Dept Radiol, St Louis, MO 63110 USA

[3] Washington Univ, Dept Chem Engn, St Louis, MO 63130 USA

来源：

SMALL | 2010年 / 6卷 / 07期

关键词：

cancer treatment; gold nanocages; photothermal transducers; plasmonic materials; FACILE SYNTHESIS; THERAPY; TOMOGRAPHY; ABLATION; NANOSTRUCTURES; PREDICTION; AGENT; PET;

D O I：

10.1002/smll.200902216

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Gold nanocages represent a new class of nanomaterials with compact size and tunable optical properties in the near-infrared region. They passively accumulate in the tumor after intravenous injection. By exposing tumors to a near-infrared diode laser, the photothermal effect of the Au nanocages selectively destroys tumor tissue with minimum damage to the surrounding healthy tissue. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：811 / 817

页数：7

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