C-reactive protein is a bystander of cardiovascular disease

被引：46

作者：

Anand, Sonia S. ^{[1
]}

Yusuf, Salim ^{[1
]}

机构：

[1] McMaster Univ, Populat Hlth Res Inst, Hamilton, ON L8L 2X2, Canada

来源：

EUROPEAN HEART JOURNAL | 2010年 / 31卷 / 17期

关键词：

C-reactive protein; CORONARY-HEART-DISEASE; RISK; CRP; PREDICTION; EVENTS; ATHEROSCLEROSIS; ROSUVASTATIN; INFLAMMATION; ASSOCIATION; PREVENTION;

D O I：

10.1093/eurheartj/ehq242

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A large number of studies have evaluated the association of hs-C-reactive protein with atherosclerosis and coronary heart disease (CHD) in mechanistic, genetic, population-based studies, as well as clinical trials. This paper reviews the collective evidence to determine if hs-C-reactive protein is part of the causal pathway of atherosclerosis and CHD or whether it is a bystander.

引用

页码：2092 / U25

页数：6

共 33 条

[1] C-reactive protein as a screening test for cardiovascular risk in a multiethnic population [J].

Anand, SS ;

Razak, F ;

Yi, QL ;

Davis, B ;

Jacobs, R ;

Vuksan, V ;

Lonn, E ;

Teo, K ;

McQueen, M ;

Yusuf, S .

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2004, 24 (08) :1509-1515

[2] Comparative impact of multiple biomarkers and N-terminal pro-brain natriuretic peptide in the context of conventional risk factors for the prediction of recurrent cardiovascular events in the Heart Outcomes Prevention Evaluation (HOPE) study [J].

Blankenberg, Stefan ;

McQueen, Matthew J. ;

Smieja, Marek ;

Pogue, Janice ;

Balion, Cynthia ;

Lonn, Eva ;

Rupprecht, Hans J. ;

Bickel, Christoph ;

Tiret, Laurence ;

Cambien, Francois ;

Gerstein, Hertzel ;

Muenzel, Thomas ;

Yusuf, Salim .

CIRCULATION, 2006, 114 (03) :201-208

[3] C-Reactive Protein as a Risk Factor for Coronary Heart Disease: A Systematic Review and Meta-analyses for the US Preventive Services Task Force [J].

Buckley, David I. ;

Fu, Rongwei ;

Freeman, Michele ;

Rogers, Kevin ;

Helfand, Mark .

ANNALS OF INTERNAL MEDICINE, 2009, 151 (07) :483-W161

[4] Insight into the nature of the CRP-coronary event association using Mendelian randomization [J].

Casas, Juan P. ;

Shah, Tina ;

Cooper, Jackie ;

Hawe, Emma ;

McMahon, Alex D. ;

Gaffney, Dairena ;

Packard, Christopher J. ;

O'Reilly, Denis S. ;

Juhan-Vague, Irene ;

Yudkin, John S. ;

Tremoli, Elena ;

Margaglione, Maurizio ;

Di Minno, Giovanni ;

Hamsten, Anders ;

Kooistra, Teake ;

Stephens, Jeffrey W. ;

Hurel, Steven J. ;

Livingstone, Shona ;

Colhoun, Helen M. ;

Miller, George J. ;

Bautista, Leonelo E. ;

Meade, Tom ;

Sattar, Naveed ;

Humphries, Steve E. ;

Hingorani, Aroon D. .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2006, 35 (04) :922-931

[5] Collaborative pooled analysis of data on C-reactive protein gene variants and coronary disease: judging causality by Mendelian randomisation [J].

Danesh, J. ;

CRP CHD Genet Collaborat ;

Hingorani, A. ;

Wensley, F. ;

Casas, J. P. ;

Smeeth, L. ;

Samani, N.J. ;

Hall, A. ;

Whincup, P. ;

Morris, R. ;

Lawlor, D.A. ;

Smith, G. Davey ;

Timpson, N. ;

Ebrahim, S. ;

Brown, M. ;

Sandhu, M. ;

Reiner, A. ;

Psaty, B. ;

Lange, L. ;

Cushman, M. ;

Tracy, R. ;

Nordestgaard, B.G. ;

Tybjaerg-Hansen, A. ;

Zacho, J. ;

Hung, J. ;

Thompson, P. ;

Beilby, J. ;

Palmer, L.J. ;

Fowkes, G. ;

Lowe, G. ;

Tzoulaki, I. ;

Kumari, M. ;

Overvad, K. ;

Khaw, K.T. ;

Benjamin, E.J. ;

Larson, M.G. ;

Yamamoto, J.F. ;

Chiodini, B. ;

Franzosi, M. ;

Norman, P.E. ;

Hankey, G.J. ;

Jamrozik, K. ;

Palmer, L. ;

Rimm, E. ;

Pai, J. ;

Heckbert, S. ;

Bis, J. ;

Yusuf, S. ;

Anand, S. ;

Engert, J. .

EUROPEAN JOURNAL OF EPIDEMIOLOGY, 2008, 23 (08) :531-540

[6] C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease [J].

Danesh, J ;

Wheeler, JG ;

Hirschfield, GM ;

Eda, S ;

Eiriksdottir, G ;

Rumley, A ;

Lowe, GDO ;

Pepys, MB ;

Gudnason, V .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (14) :1387-1397

[7] Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease [J].

Elliott, Paul ;

Chambers, John C. ;

Zhang, Weihua ;

Clarke, Robert ;

Hopewell, Jemma C. ;

Peden, John F. ;

Erdmann, Jeanette ;

Braund, Peter ;

Engert, James C. ;

Bennett, Derrick ;

Coin, Lachlan ;

Ashby, Deborah ;

Tzoulaki, Ioanna ;

Brown, Ian J. ;

Mt-Isa, Shahrul ;

McCarthy, Mark I. ;

Peltonen, Leena ;

Freimer, Nelson B. ;

Farrall, Martin ;

Ruokonen, Aimo ;

Hamsten, Anders ;

Lim, Noha ;

Froguel, Philippe ;

Waterworth, Dawn M. ;

Vollenweider, Peter ;

Waeber, Gerard ;

Jarvelin, Marjo-Riitta ;

Mooser, Vincent ;

Scott, James ;

Hall, Alistair S. ;

Schunkert, Heribert ;

Anand, Sonia S. ;

Collins, Rory ;

Samani, Nilesh J. ;

Watkins, Hugh ;

Kooner, Jaspal S. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (01) :37-48

[8] ENVIRONMENT AND DISEASE - ASSOCIATION OR CAUSATION [J].

HILL, AB .

PROCEEDINGS OF THE ROYAL SOCIETY OF MEDICINE-LONDON, 1965, 58 (05) :295-+

[9] C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis [J].

Kaptoge, Stephen ;

Di Angelantonio, Emanuele ;

Lowe, Gordon ;

Pepys, Mark B. ;

Thompson, Simon G. ;

Collins, Rory ;

Danesh, John ;

Tipping, R. W. ;

Ford, C. E. ;

Pressel, S. L. ;

Walldius, G. ;

Jungner, I. ;

Folsom, A. R. ;

Chambless, L. ;

Ballantyne, C. M. ;

Panagiotakos, D. ;

Pitsavos, C. ;

Chrysohoou, C. ;

Stefanadis, C. ;

Knuiman, M. W. ;

Goldbourt, U. ;

Benderly, M. ;

Tanne, D. ;

Whincup, P. ;

Wannamethee, S. G. ;

Morris, R. W. ;

Kiechl, S. ;

Willeit, J. ;

Mayr, A. ;

Schett, G. ;

Wald, N. ;

Ebrahim, S. ;

Lawlor, D. ;

Yarnell, J. ;

Gallacher, J. ;

Casiglia, E. ;

Tikhonoff, V. ;

Nietert, P. J. ;

Sutherland, S. E. ;

Bachman, D. L. ;

Keil, J. E. ;

Cushman, M. ;

Psaty, B. M. ;

Tracy, R. ;

Tybjaerg-Hansen, A. ;

Nordestgaard, B. G. ;

Zacho, J. ;

Frikke-Schmidt, R. ;

Giampaoli, S. ;

Palmieri, L. .

LANCET, 2010, 375 (9709) :132-140

[10] Rosuvastatin in older patients with systolic heart failure [J].

Kjekshus, John ;

Apetrei, Eduard ;

Barrios, Vivencio ;

Boehm, Michael ;

Cleland, John G. F. ;

Cornel, Jan H. ;

Dunselman, Peter ;

Fonseca, Candida ;

Goudev, Assen ;

Grande, Peer ;

Gullestad, Lars ;

Hjalmarson, Ake ;

Hradec, Jaromir ;

Janosi, Andras ;

Kamensky, Gabriel ;

Komajda, Michel ;

Korewicki, Jerzy ;

Kuusi, Timo ;

Mach, Francois ;

Mareev, Vyacheslav ;

McMurray, John J. V. ;

Ranjith, Naresh ;

Schaufelberger, Maria ;

Vanhaecke, Johan ;

van Veldhuisen, Dirk J. ;

Waagstein, Finn ;

Wedel, Hans ;

Wikstrand, John .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (22) :2248-2261

← 1 2 3 4 →