Equilibrium surface properties of lipid mixtures of retinal, phosphatidylcholine and fatty acid derivatives at the air/water interface

被引:7
作者
Angelova, A
De Coninck, J
Ionov, R
机构
[1] Inst Biophys, Sofia, Bulgaria
[2] Univ Mons, Fac Sci, B-7000 Mons, Belgium
[3] Inst Phys Appl, Sofia, Bulgaria
来源
SUPRAMOLECULAR SCIENCE | 1997年 / 4卷 / 3-4期
关键词
surface properties; air/water interface; lipid mixture;
D O I
10.1016/S0968-5677(97)00006-0
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The miscibilities of phosphatidylcholine, retinal and saturated fatty acid derivatives in surface phases at the air/water interface are investigated on the basis of the thermodynamic two-dimensional phase rule. The latter is applied to the 'collapse' pressure and the equilibrium surface pressure characteristics of binary lipid monolayers or spread amphiphilic mixtures, respectively. The equilibrium surface pressures (ESPs), at which insoluble lipid monolayers are in equilibrium with three-dimensional lipid phases, are determined by spreading of single-component or binary solutions of lipids in organic solvent up to supersaturation at the air/water interface. The kinetics of establishment of steady surface pressure values at supersaturation is followed depending on the nature of the lipid samples. ESPs and 'collapse' pressures of mixtures of dilauroylphosphatidylcholine (DLPC), all-trans retinal (t-R) and lauric acid (LA) are studied at various lipid molar ratios. The compositional phase diagrams of the ESPs and 'collapse' pressures, obtained at a constant temperature, indicate that the interfacial miscibilities of both DLPC and t-R and DLPC and LA are nonideal. Owing to its 'bulky' molecular structure and the tendency towards self-aggregation, dominated by intermolecular pi-pi interactions, the t-R component could be accommodated in the hydrophobic portion of the phospholipid membrane at mole fractions less than 0.5. The accommodation of the other neutral, rodlike fatty acid component in the DLPC matrix is probably favoured by the formation of intermolecular hydrogen bonding. Phase separation between DLPC and LA is evident from the thermodynamic results at high LA mole fractions (> 0.75) in the surface mixtures. (C) 1997 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:207 / 214
页数:8
相关论文
共 25 条
  • [1] ALSINA MA, 1988, COLLOID SURFACE, V34, P151
  • [2] 2D-3D transformations of amphiphilic monolayers influenced by intermolecular interactions: A Brewster angle microscopy study
    Angelova, A
    Vollhardt, D
    Ionov, R
    [J]. JOURNAL OF PHYSICAL CHEMISTRY, 1996, 100 (25) : 10710 - 10720
  • [3] MISCIBILITY OF ALKANOIC AND OMEGA-ANTHRYLALKANOIC ACIDS IN MONOLAYERS AT THE AIR/WATER INTERFACE STUDIED BY MEANS OF BREWSTER-ANGLE MICROSCOPY
    ANGELOVA, A
    VANDERAUWERAER, M
    IONOV, R
    VOLLHARDT, D
    DESCHRYVER, FC
    [J]. LANGMUIR, 1995, 11 (08) : 3167 - 3176
  • [4] WETTING OF HETEROGENEOUS MONOLAYER SURFACES
    ANGELOVA, A
    [J]. THIN SOLID FILMS, 1994, 243 (1-2) : 394 - 398
  • [5] DIMYRISTOYL PHOSPHATIDYLCHOLINE - EQUILIBRIUM SPREADING BEHAVIOR
    BARNES, GT
    LAWRIE, GA
    BATTERSBY, BJ
    SARGE, SM
    CAMMENGA, HK
    SCHNEIDER, PB
    [J]. THIN SOLID FILMS, 1994, 242 (1-2) : 201 - 207
  • [6] Crisp D.J., 1949, SURFACE CHEM S, P17
  • [7] DEFAY R, 1966, SURFACE TENSION ADSO, P77
  • [8] Gaines G.L., 1966, INSOLUBLE MONOLAYERS
  • [9] SURFACE CHEMISTRY OF MONOOCTADECYL PHOSPHATE AT AIR/WATER INTERFACE . A STUDY OF MOLECULAR AGGREGATION IN MONOLAYERS
    GERSHFELD, NL
    PAK, CYC
    [J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1967, 23 (02) : 215 - +
  • [10] HANDA T, 1985, PROG COLL POL SCI S, V71, P26