Different noses for different people

被引:162
作者
Menashe, I
Man, O
Lancet, D [1 ]
Gilad, Y
机构
[1] Weizmann Inst Sci, Dept Mol Genet, IL-76100 Rehovot, Israel
[2] Weizmann Inst Sci, Crown Human Genome Ctr, IL-76100 Rehovot, Israel
关键词
D O I
10.1038/ng1160
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Of more than 1,000 human olfactory receptor genes, more than half seem to be pseudogenes. We investigated whether the most recent of these disruptions might still segregate with the intact form by genotyping 51 candidate genes in 189 ethnically diverse humans. The results show an unprecedented prevalence of segregating pseudogenes, identifying one of the most pronounced cases of functional population diversity in the human genome.
引用
收藏
页码:143 / 144
页数:2
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