Comparative in vitro activities of carbapenem antimicrobial agents against 264 penicillin-resistant Streptococcus pneumoniae isolates from Korea

被引：5

作者：

Choi, Sang-Ho

Park, Su Jin

Jun, Jae-Bum

Lee, Sang-Rok

Jeon, Min-Hyuk

Kwon, Hyun-Hee

Kim, Seong Cherl

Kim, Mi-Na

Jeong, Jin-Yong

Woo, Jun Hee

Kim, Yang Soo ^{[1
]}

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Div Infect Dis, Seoul 138736, South Korea

[2] Univ Ulsan, Ctr Antimicrobial Resistance & Microbial Genet, Seoul 138736, South Korea

[3] Univ Ulsan, Coll Med, Dept Lab Med, Asan Med Ctr, Seoul 138736, South Korea

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2007年 / 58卷 / 01期

关键词：

Streptococcus pneumoniae; carbapenems; imipenem; meropenem; ertapenem; panipenem;

D O I：

10.1016/j.diagmicrobio.2006.11.017

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We compared in vitro activities of carbapenems against 264 penicillin-resistant Streptococcus pneumoniae (PRSP) isolates. The MIC50/ MIC90 (mu g/mL) values of imipenem, meropenem, ertapenem, and panipenem were 1/1, 0.25/0.25, 0.25/0.5, and 0.125/0.25, respectively. The susceptibility rates to imipenem, meropenem, and ertapenern were 0%, 85.2%, and 99.6%, respectively. Compared with imipenem and meropenem, ertapenem and pampenem had better in vitro activities against PRSP. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：141 / 143

页数：3

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