Phenylpropanoid and flavonoids from osteoprotective fraction of Drynaria fortunei

被引：38

作者：

Wang, Xin-Luan ^{[2
]}

Wang, Nai-Li ^{[3
]}

Gao, Hao ^{[1
]}

Zhang, Ge ^{[2
]}

Qin, Ling ^{[2
]}

Wong, Man-Sau ^{[4
]}

Yao, Xin-Sheng ^{[1
]}

机构：

[1] Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Coll Pharm, Guangzhou 510632, Guangdong, Peoples R China

[2] Chinese Univ Hong Kong, Dept Orthoped & Traumatol, Musculoskeletal Res Lab, Hong Kong, Hong Kong, Peoples R China

[3] Tsinghua Univ, Key Lab New Drugs Res TCM, Shenzhen Res Inst, Shenzhen 518057, Peoples R China

[4] Hong Kong Polytech Univ, Open Lab Chirotechnol, Inst Mol Technol Drug Discovery & Synth, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2010年 / 24卷 / 13期

基金：

美国国家科学基金会;

关键词：

Drynaria fortunei; phenylpropanoid; chalcone; flavanone; flavonol;

D O I：

10.1080/14786410902991860

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

A new phenylpropanoid (1), 12-O-caffeoyl-12-hydroxyldodecanoic acid, and a new chalcone (2), 3'-lavandulyl-4-methoxyl-2,2',4',6'-tetrahydroxylchalcone, together with eight known compounds including one chalcone (3), five flavanones (4-8) and two flavonols (9, 10), have been isolated from one of the osteoprotective fractions of Drynaria fortunei (Kunze) J. Sm., which is used as a folk medicine for the treatment of osteoporosis. All these compounds were found for the first time from the genus Drynaria. The structures of the new compounds were elucidated on the basis of spectroscopic analysis.

引用

页码：1206 / 1213

页数：8

共 14 条

[1]

[Anonymous], REV BRASILEIRA FARMA

[2]

Proliferative effects of flavan-3-ols and propelargonidins from rhizomes of Drynaria fortunei on MCF-7 and osteoblastic cells [J].