Breaking the affinity ceiling for antibodies and T cell receptors

[1] Affinity dependence of the B cell response to antigen: A threshold, a ceiling, and the importance of off-rate [J]. IMMUNITY, 1998, 8 (06) : 751 - 759

[2] RADIATION CHIMAERA, HOST H-2 ANTIGENS DETERMINE IMMUNE RESPONSIVENESS OF DONOR CYTOTOXIC CELLS [J]. NATURE, 1977, 269 (5627) : 417 - 418

[3] Optimal screening of surface-displayed polypeptide libraries [J]. BIOTECHNOLOGY PROGRESS, 1998, 14 (01) : 55 - 62

[4] Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) : 10701 - 10705

[5] Yeast surface display for screening combinatorial polypeptide libraries [J]. NATURE BIOTECHNOLOGY, 1997, 15 (06) : 553 - 557

[6] T cell affinity maturation by selective expansion during infection [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (04) : 701 - 709

[7] MATING TYPE-SPECIFIC CELL-CELL RECOGNITION OF SACCHAROMYCES-CEREVISIAE - CELL-WALL ATTACHMENT AND ACTIVE-SITES OF A-AGGLUTININ AND ALPHA-AGGLUTININ [J]. EMBO JOURNAL, 1994, 13 (20) : 4737 - 4744

[8] VARIATION IN AFFINITIES OF ANTIBODIES DURING IMMUNE RESPONSE [J]. BIOCHEMISTRY, 1964, 3 (07) : 996 - &

[9] FERSHT A, 1977, ENZYME STRUCTURE MEC, P285

[10] FOOTE J, 1995, P ANTL ACAD SCI US, V92, P1054

[1] Affinity dependence of the B cell response to antigen: A threshold, a ceiling, and the importance of off-rate [J]. IMMUNITY, 1998, 8 (06) : 751 - 759

[2] RADIATION CHIMAERA, HOST H-2 ANTIGENS DETERMINE IMMUNE RESPONSIVENESS OF DONOR CYTOTOXIC CELLS [J]. NATURE, 1977, 269 (5627) : 417 - 418

[3] Optimal screening of surface-displayed polypeptide libraries [J]. BIOTECHNOLOGY PROGRESS, 1998, 14 (01) : 55 - 62

[4] Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (20) : 10701 - 10705

[5] Yeast surface display for screening combinatorial polypeptide libraries [J]. NATURE BIOTECHNOLOGY, 1997, 15 (06) : 553 - 557

[6] T cell affinity maturation by selective expansion during infection [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1999, 189 (04) : 701 - 709

[7] MATING TYPE-SPECIFIC CELL-CELL RECOGNITION OF SACCHAROMYCES-CEREVISIAE - CELL-WALL ATTACHMENT AND ACTIVE-SITES OF A-AGGLUTININ AND ALPHA-AGGLUTININ [J]. EMBO JOURNAL, 1994, 13 (20) : 4737 - 4744

[8] VARIATION IN AFFINITIES OF ANTIBODIES DURING IMMUNE RESPONSE [J]. BIOCHEMISTRY, 1964, 3 (07) : 996 - &

[9] FERSHT A, 1977, ENZYME STRUCTURE MEC, P285

[10] FOOTE J, 1995, P ANTL ACAD SCI US, V92, P1054