Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece

被引：53

作者：

Syrogiannopoulos, GA

Grivea, IN

Tait-Kamradt, A

Katopodis, GD

Beratis, NG

Sutcliffe, J

Appelbaum, PC

Davies, TA

机构：

[1] Univ Patras, Sch Med, Gen Univ Hosp, Dept Pediat, Patras 26500, Greece

[2] Pfizer Inc, Global Res & Dev, Dept Infect Dis, Groton, CT USA

[3] Milton S Hershey Med Ctr, Dept Pathol, Philadelphia, PA USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 01期

关键词：

D O I：

10.1128/AAC.45.1.342-344.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In a serotype 11A clone of erythromycin-resistant pneumococci isolated from young Greek carriers, we identified the nucleotide sequence of erm(A), a methylase gene previously described as erm(TR) in Streptococcus pyogenes. The erm(A) pneumococci were resistant to 14- and 15-member macrolides, inducibly resistant to clindamycin, and susceptible to streptogramin B. To our knowledge, this is the first identification of resistance to erythromycin in S. pneumoniae attributed solely to the carriage of the erm(A) gene.

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页码：342 / 344

页数：3

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