Animal models of exocrine pancreatic cancer

被引：24

作者：

Hotz, HG ^{[1
]}

Hines, OJ ^{[1
]}

Foitzik, T ^{[1
]}

Reber, HA ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Surg, Los Angeles, CA 90095 USA

来源：

INTERNATIONAL JOURNAL OF COLORECTAL DISEASE | 2000年 / 15卷 / 03期

关键词：

pancreatic cancer; exocrine animal model;

D O I：

10.1007/s003840000229

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Clinically and biologically relevant animal models are mandatory to further evaluate both the pathophysiology and novel strategies for diagnosis and treatment of exocrine pancreatic cancer. This review briefly summarizes the features of human pancreatic cancer in order to define requirements for animal models of the disease. The described model systems in rodents include pancreatic cancer induced by chemicals, pancreatic cancer in transgenic, and immunodeficient animals.

引用

页码：136 / 143

页数：8

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