Nanomaterials as Analytical Tools for Genosensors

被引:72
作者
Abu Salah, Khaled [1 ]
Alrokyan, Salman A. [1 ]
Khan, Muhammad Naziruddin [1 ]
Ansari, Anees Ahmad [1 ]
机构
[1] King Saud Univ, King Abdullah Inst Nanotechnol, Riyadh 11451, Saudi Arabia
来源
SENSORS | 2010年 / 10卷 / 01期
关键词
nanomaterials; oligonucleotides; ZnO; carbon nanotubes; conducting polymers; ELECTROCHEMICAL DNA BIOSENSORS; WALLED CARBON NANOTUBES; FILM-MODIFIED ELECTRODE; BAR CODE METHOD; ELECTRICAL DETECTION; GOLD NANOPARTICLES; CONDUCTING POLYMERS; SEQUENCE DETECTION; AU NANOPARTICLES; COLLOIDAL GOLD;
D O I
10.3390/s100100963
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Nanomaterials are being increasingly used for the development of electrochemical DNA biosensors, due to the unique electrocatalytic properties found in nanoscale materials. They offer excellent prospects for interfacing biological recognition events with electronic signal transduction and for designing a new generation of bioelectronic devices exhibiting novel functions. In particular, nanomaterials such as noble metal nanoparticles (Au, Pt), carbon nanotubes (CNTs), magnetic nanoparticles, quantum dots and metal oxide nanoparticles have been actively investigated for their applications in DNA biosensors, which have become a new interdisciplinary frontier between biological detection and material science. In this article, we address some of the main advances in this field over the past few years, discussing the issues and challenges with the aim of stimulating a broader interest in developing nanomaterial-based biosensors and improving their applications in disease diagnosis and food safety examination.
引用
收藏
页码:963 / 993
页数:31
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