Impact of hot flashes on quality of life among postmenopausal women being treated for breast cancer

被引:84
作者
Stein, KD
Jacobsen, PB
Hann, DM
Greenberg, H
Lyman, G
机构
[1] Amer Canc Soc, Behav Res Ctr, Atlanta, GA 30329 USA
[2] Univ S Florida, H Lee Moffit Canc Ctr & Res Inst, Psychosocial Oncol Program, Tampa, FL USA
[3] Univ S Florida, H Lee Moffit Canc Ctr & Res Inst, Comprehens Breast Canc Program, Tampa, FL USA
关键词
hot flashes; breast cancer fatigue; quality of life;
D O I
10.1016/S0885-3924(00)00142-1
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Hot flashes are among the most commonly reported symptoms among women who have completed treatment for breast cancer. Relatively little is known, however; about hotflashes among women while they are undergoing beast cancer treatment. The present study investigated the prevalence and severity of hotflashes of women during chemotherapy and radiotherapy for breast cancer We also sought to identify the medical, demographic, and treatment correlates of hot flashes during treatment and to document the impact of hot flashes on quality of life. Seventy postmenopausal women, with breast cancer completed a self-report questionnaire packet during chemotherapy and radiotherapy. Forty percent (n = 28) reported hotflashes during the week prior to assessment. Of the 28 women endorsing hot flashes, 25 % (n = 7) rated them as severe, 39% (n = 11) rated them as moderate, and 36% (n = 10) rated them as mild. Women with hot flashes were significantly (p < 0.05) younger and reported significantly (p < 0.001) more fatigue, poorer sleep quality, and poorer physical health compared to women without hot flashes. Multivariate analyses revealed that, even after controlling for relevant medical, demographic, and treatment variables, the prevalence of hot flashes significantly (p < 0. 05) predicted poorer sleep quality, more fatigue, and worse physical health. The results indicate that hot flashes are experienced by a sizable percentage of postmenopausal breast cancer patients as they undergo treatment. Hot flashes during cancer treatment appear to have a negative impact upon patient quality of life that may be due, in part, to fatigue and interference with sleep. Future research should seek to evaluate interventions to relieve hot flashes during beast cancer treatment as a means of improving. patient quality of life. (C) U.S. Cancer Pain Relief Committee, 2000.
引用
收藏
页码:436 / 445
页数:10
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