Progression from single to multiple islet autoantibodies often occurs soon after seroconversion: implications for early screening

被引：36

作者：

Chmiel, Ruth ^{[1
,2
]}

Giannopoulou, Eleni Z. ^{[1
,2
,3
]}

Winkler, Christiane ^{[1
,2
,3
]}

Achenbach, Peter ^{[1
,2
,3
]}

Ziegler, Anette-Gabriele ^{[1
,2
,3
]}

Bonifacio, Ezio ^{[4
,5
,6
]}

机构：

[1] Helmholtz Zentrum Munchen, Diabet Res Inst, D-85764 Neuherberg, Germany

[2] Tech Univ Munich, Klinikum Rechts Isar, Forschergrp Diabet, D-85764 Neuherberg, Germany

[3] Forschergrp Diabet eV, Neuherberg, Germany

[4] Tech Univ Dresden, Ctr Regenerat Therapies Dresden, D-01062 Dresden, Germany

[5] German Ctr Diabet Res DZD, Paul Langerhans Inst Dresden, Dresden, Germany

[6] Helmholtz Zentrum Munchen, Inst Diabet & Obes, D-85764 Neuherberg, Germany

来源：

DIABETOLOGIA | 2015年 / 58卷 / 02期

关键词：

Incidence; Multiple islet autoantibodies; Type; 1; diabetes; CHILDREN; RISK;

D O I：

10.1007/s00125-014-3443-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：411 / 413

页数：3

共 5 条

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[3] Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk [J].

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[5] Seroconversion to Multiple Islet Autoantibodies and Risk of Progression to Diabetes in Children [J].

Ziegler, Anette G. ;

Rewers, Marian ;

Simell, Olli ;

Simell, Tuula ;

Lempainen, Johanna ;

Steck, Andrea ;

Winkler, Christiane ;

Ilonen, Jorma ;

Veijola, Riitta ;

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Eisenbarth, George S. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 309 (23) :2473-2479

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