Production technologies for monoclonal antibodies and their fragments

被引：107

作者：

Andersen, DC ^{[1
]}

Reilly, DE ^{[1
]}

机构：

[1] Genentech Inc, San Francisco, CA 94080 USA

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2004年 / 15卷 / 05期

关键词：

D O I：

10.1016/j.copbio.2004.08.002

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In recent years, monoclonal antibodies have emerged as an increasingly important class of human therapeutics. A variety of forms of antibodies, including fragments such as Fabs, Fab'(2)s and single-chain Fvs, are also being evaluated for a range of different purposes. A variety of expression systems and improvements within these systems have been developed to address these growing and diverse needs.

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收藏

页码：456 / 462

页数：7

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