West Nile virus: crossing the blood-brain barrier

被引：60

作者：

Diamond, MS ^{[1
]}

Klein, RS

机构：

[1] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Dept Mol Microbiol, St Louis, MO 63110 USA

[3] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

[4] Washington Univ, Sch Med, Dept Anat & Neurobiol, St Louis, MO 63110 USA

来源：

NATURE MEDICINE | 2004年 / 10卷 / 12期

关键词：

D O I：

10.1038/nm1204-1294

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A study in mice traces the path of West Nile virus into the brain. Viral replication in peripheral tissues triggers a Toll-like receptor inflammatory response that alters the blood-brain barrier (pages 1366–1373).

引用

页码：1294 / 1295

页数：2

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