Clear cell sarcoma of the ileum - The crucial role of cytogenetics for the diagnosis

被引：46

作者：

Donner, LR ^{[1
]}

Trompler, RA ^{[1
]}

Dobin, S ^{[1
]}

机构：

[1] Texas A&M Univ, Scott & White Mem Hosp & Clin, Dept Pathol, Hlth Sci Ctr,Coll Med, Temple, TX 76508 USA

来源：

AMERICAN JOURNAL OF SURGICAL PATHOLOGY | 1998年 / 22卷 / 01期

关键词：

clear cell sarcoma; ultrastructure; immunohistochemistry; cytogenetics;

D O I：

10.1097/00000478-199801000-00016

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We report a case of clear cell sarcoma that arose in the ileum and metastasized to the liver. The tumor cells did not contain melanin or glycogen; expressed S-100 protein, but not HMB45; and contained possible atypical melanosomes when examined by electron microscopy. They carried a clonal chromosomal rearrangement: 50,XY,t(2;7)(q37;q22),+8,+8,+9,+11, t(12;22)(q13;q12). The diagnosis was greatly facilitated by the cytogenetic analysis. The translocation t(12;22)(q13;q12-13) has been reported as specific for clear cell sarcomas.

引用

页码：121 / 124

页数：4

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