Chronic progressive leukoencephalopathy in adult celiac disease

被引：24

作者：

Beyenburg, S

Scheid, B

Deckert-Schlüter, M

Lagrèze, HL

机构：

[1] Univ Bonn, Dept Neuropathol, D-53105 Bonn, Germany

[2] Klinikum Leverkusen, Dept Neurol, Leverkusen, Germany

来源：

NEUROLOGY | 1998年 / 50卷 / 03期

关键词：

D O I：

10.1212/WNL.50.3.820

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Progressive leukoencephalopathy developed in a patient with adult celiac disease. Neurologic abnormalities appeared 4 years after the gastrointestinal manifestations despite a gluten-free diet and replacement of vitamins. Brain MRI showed marked confluent white matter abnormalities, and stereotactic brain biopsy revealed chronic leukoencephalopathy. Treatment with IV steroids and immunoglobulins did not stop disease progression. Celiac disease should be considered in the differential diagnosis of the leukoencephalopathies.

引用

页码：820 / 822

页数：3

共 9 条

[1] PROGRESSIVE MYOCLONIC ATAXIA ASSOCIATED WITH CELIAC-DISEASE - THE MYOCLONUS IS OF CORTICAL ORIGIN, BUT THE PATHOLOGY IS IN THE CEREBELLUM [J].

BHATIA, KP ;

BROWN, P ;

GREGORY, R ;

LENNOX, GG ;

MANJI, H ;

THOMPSON, PD ;

ELLISON, DW ;

MARSDEN, CD .

BRAIN, 1995, 118 :1087-1093

[2] Leukoencephalopathy associated with cobalamin deficiency [J].

Chatterjee, A ;

Yapundich, R ;

Palmer, CA ;

Marson, DC ;

Mitchell, GW .

NEUROLOGY, 1996, 46 (03) :832-834

[3] Does cryptic gluten sensitivity play a part in neurological illness? [J].

Hadjivassiliou, M ;

Gibson, A ;

DaviesJones, GAB ;

Lobo, AJ ;

Stephenson, TJ ;

MilfordWard, A .

LANCET, 1996, 347 (8998) :369-371

[4]

KEPES JJ, 1975, NEUROLOGY, V25, P1006

[5]

Lu C S, 1986, Mov Disord, V1, P209, DOI 10.1002/mds.870010306

[6] BILATERAL OCCIPITAL CALCIFICATION, EPILEPSY AND CELIAC-DISEASE - CLINICAL AND NEUROIMAGING FEATURES OF A NEW SYNDROME [J].

MAGAUDDA, A ;

DALLABERNARDINA, B ;

DEMARCO, P ;

SFAELLO, Z ;

LONGO, M ;

COLAMARIA, V ;

DANIELE, O ;

TORTORELLA, G ;

TATA, MA ;

DIPERRI, R ;

MEDURI, M .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1993, 56 (08) :885-889

[7]

MARSH MN, 1995, Q J MED, V85, P9

[8]

Muller AF, 1996, AM J GASTROENTEROL, V91, P1430

[9]

MUMFORD CJ, 1996, J NEUROL NEUROSUR PS, V60, P255

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