Diastereoselective formal synthesis of the antifungal agent, (+)-preussin.: A new entry to chiral pyrrolidines

被引：20

作者：

de Armas, P

García-Tellado, F

Marrero-Tellado, JJ

Robles, J

机构：

[1] Univ La Laguna, CSIC, Inst Prod Nat & Agrobiol, La Laguna 38206, Tenerife, Spain

[2] Univ La Laguna, Inst Univ Bioorgan Antonio Gonzalez, Inst Prod Nat & Agrobiol, La Laguna 38206, Tenerife, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 1-2期

关键词：

D O I：

10.1016/S0040-4039(97)10468-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A formal total synthesis of (+)-Preussin was achieved by using D-mannose as the starting material. The key step involved diastereoselective addition of allyltrimethylsilane to the bicyclic ketal 5. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：131 / 134

页数：4

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