A tuneable and highly-parallel picolitre-dispenser based on direct liquid displacement

被引：34

作者：

de Heij, B

Steinert, C

Sandmaier, H

Zengerle, R

机构：

[1] Univ Freiburg, IMTEK, D-79110 Freiburg, Germany

[2] HSG, IMIT, D-78052 Villingen Schwenningen, Germany

来源：

SENSORS AND ACTUATORS A-PHYSICAL | 2003年 / 103卷 / 1-2期

关键词：

highly-parallel; picolitre-dispenser; bio-molecule; microfluidics;

D O I：

10.1016/S0924-4247(02)00321-7

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We present a new method for the highly-parallel and simultaneous delivery of a multitude of reagents in the picolitre range. This method is based on direct displacement of the liquids using an elastomer-stamp, which simultaneously actuates up to 96 dosing channels, at a pitch of 500 mum. We were able to tune droplet volume from 100 to 700 pl and droplet speed from 0.3 to 4 m/s using printheads with 50 mum diameter nozzles. In contrast to all other inkjet techniques the new direct displacement method enables the precise control of dispensing quantity in the picolitre range regardless of reagent viscosity. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：88 / 92

页数：5