Learning and forgetting in schizophrenia

被引:51
作者
Gold, JM [1 ]
Rehkemper, G [1 ]
Binks, SW [1 ]
Carpenter, CJ [1 ]
Fleming, K [1 ]
Goldberg, TE [1 ]
Weinberger, DR [1 ]
机构
[1] NIMH, St Elizabeths Hosp, Ctr Neurosci, Clin Res Serv Branch,Div Intramural Res Programs, Washington, DC 20032 USA
关键词
D O I
10.1037//0021-843X.109.3.534
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Recent studies of patients with schizophrenia have consistently demonstrated marked deficits on measures of initial learning. However, contradictory results have been reported concerning retention and forgetting. The present study examined the level of initial and delayed recall of stories and visual figures in a group of 76 patients with schizophrenia and 51 normal controls. schizophrenia patients demonstrated marked impairments in initial and delayed recall as well as significantly worse percentage retention scores. However. schizophrenia patients and healthy controls individually matched on level of initial recall bad nearly identical delayed recall performance. The results suggest a primary deficit in the initial acquisition of information rather than an accelerated rate of forgetting in schizophrenia.
引用
收藏
页码:534 / 538
页数:5
相关论文
共 36 条
[1]   MEMORY AND FRONTAL-LOBE DYSFUNCTION IN SCHIZOPHRENIA AND SCHIZOAFFECTIVE DISORDER [J].
BEATTY, WW ;
JOCIC, Z ;
MONSON, N ;
STATON, RD .
JOURNAL OF NERVOUS AND MENTAL DISEASE, 1993, 181 (07) :448-453
[2]   EVALUATING FORGETTING CURVES PSYCHOLOGICALLY [J].
BOGARTZ, RS .
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-LEARNING MEMORY AND COGNITION, 1990, 16 (01) :138-148
[3]   The efficacy of 2 different dosages of methylphenidate in treating adults with attention-deficit hyperactivity disorder [J].
Bouffard, R ;
Hechtman, L ;
Minde, K ;
Iaboni-Kassab, F .
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE, 2003, 48 (08) :546-554
[4]   Imaging cognition: An empirical review of PET studies with normal subjects [J].
Cabeza, R ;
Nyberg, L .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1997, 9 (01) :1-26
[5]   PERFORMANCE OF LONG-STAY SCHIZOPHRENICS AFTER DRUG-WITHDRAWAL ON MATCHED IMMEDIATE AND DELAYED RECALL TASKS [J].
CALEV, A ;
NIGAL, D ;
KUGELMASS, S ;
WELLER, MPI ;
LERER, B .
BRITISH JOURNAL OF CLINICAL PSYCHOLOGY, 1991, 30 :241-245
[6]   EVIDENCE FOR DISTINCT VERBAL MEMORY PATHOLOGIES IN SEVERELY AND MILDLY DISTURBED SCHIZOPHRENICS [J].
CALEV, A ;
VENABLES, PH ;
MONK, AF .
SCHIZOPHRENIA BULLETIN, 1983, 9 (02) :247-264
[7]  
Cohen J., 1998, Statistical Power Analysis for the Behavioral Sciences, V2nd
[8]  
Delis D. C., 1987, California Verbal Learning Test Manual, DOI [10.1037/t15072-000, DOI 10.1037/T15072-000]
[9]   FORGETTING IN HM - A 2ND LOOK [J].
FREED, DM ;
CORKIN, S ;
COHEN, NJ .
NEUROPSYCHOLOGIA, 1987, 25 (03) :461-471
[10]   MEMORY AND INTELLIGENCE IN LATERALIZED TEMPORAL-LOBE EPILEPSY AND SCHIZOPHRENIA [J].
GOLD, JM ;
BLAXTON, TA ;
HERMANN, BP ;
RANDOLPH, C ;
FEDIO, P ;
GOLDBERG, TE ;
THEODORE, WH ;
WEINBERGER, DR .
SCHIZOPHRENIA RESEARCH, 1995, 17 (01) :59-65