The Na/K pump, Cl ion, and osmotic stabilization of cells

被引：110

作者：

Armstrong, CM ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Physiol, Philadelphia, PA 19104 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2003年 / 100卷 / 10期

关键词：

D O I：

10.1073/pnas.0931278100

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An equation for membrane voltage is derived that takes into account the electrogenicity of the Na/K pump and is valid dynamically, as well as in the steady state. This equation is incorporated into a model for the osmotic stabilization of cells. The results emphasize the role of the pump and membrane voltage in lowering internal Cl- concentration, thus making osmotic room for vital substances that must be sequestered in the cell.

引用

页码：6257 / 6262

页数：6

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