Synthesis and biological evaluation of 2,6-di-tert-butylphenol hydrazones as 5-lipoxygenase inhibitors

被引：14

作者：

Cuadro, AM

Valenciano, J

Vaquero, JJ

Alvarez-Builla, J ^{[1
]}

Sunkel, C

de Casa-Juana, MF

Ortega, MP

机构：

[1] Univ Alcala de Henares, Dept Quim Organ, Alcala De Henares 28871, Madrid, Spain

[2] Labs Alter SA, Dept Invest, Madras, Tamil Nadu, India

来源：

BIOORGANIC & MEDICINAL CHEMISTRY | 1998年 / 6卷 / 02期

关键词：

D O I：

10.1016/S0968-0896(97)10018-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

The preparation of hydrazone derivatives of 3,5-di-tert-butyl-4-hydroxybenzaldehyde and the inhibition of 5-lipoxygenase (5-LO) by these compounds is discussed. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：173 / 180

页数：8

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