Control of cell proliferation by Myc

被引:209
作者
Bouchard, C [1 ]
Staller, P [1 ]
Eilers, M [1 ]
机构
[1] Univ Marburg, Inst Mol Biol & Tumour Res, D-35032 Marburg, Germany
关键词
D O I
10.1016/S0962-8924(98)01251-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Myc proteins are key regulators of mammalian cell proliferation. They are transcription factors that activate genes as part of a heterodimeric complex with the protein Max. This review summarizes recent progress in understanding how Myc stimulates cell proliferation and how this might contribute to cellular transformation and tumorigenesis.
引用
收藏
页码:202 / 206
页数:5
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