Enediolates and dienediolates of carboxylic acids in synthesis.: Synthesis of β,γ-epoxyacids from α-chloroketones.

被引：10

作者：

Brun, EM ^{[1
]}

Gil, S ^{[1
]}

Mestres, R ^{[1
]}

Parra, M ^{[1
]}

Villar, F ^{[1
]}

机构：

[1] Univ Valencia, Dept Quim Organ, Valencia, Spain

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 09期

关键词：

D O I：

10.1016/S0040-4039(97)10726-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithium dienolates of saturated or alpha,beta-unsaturated acids react with alpha-chloroketones provide a convenient method for preparation of highly sustituted beta,gamma-epoxyacids. These highly reactive compounds lead in most cases to variable ammounts of the corresponding beta-lactones and allylic alcohols. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1055 / 1058

页数：4

共 19 条

[1] TRIENEDIOLATES OF HEXADIENOIC ACIDS IN SYNTHESIS - ADDITION TO UNSATURATED-KETONES - A CONVERGENT APPROACH TO THE SYNTHESIS OF RETINOIC ACIDS [J].