Changing the Mindset in Life Sciences Toward Translation: A Consensus

被引：37

作者：

Duda, Georg N. ^{[1
,2
]}

Grainger, David W. ^{[3
]}

Frisk, Megan L. ^{[4
]}

Bruckner-Tuderman, Leena ^{[5
,6
]}

Carr, Andrew ^{[7
]}

Dirnagl, Ulrich ^{[8
,9
]}

Einhaeupl, Karl Max ^{[10
]}

Gottschalk, Stephen ^{[11
]}

Gruskin, Elliott ^{[12
]}

Huber, Christoph ^{[13
]}

June, Carl H. ^{[14
]}

Mooney, David J. ^{[15
,16
]}

Rietschel, Ernst Th. ^{[17
]}

Schuette, Georg ^{[18
]}

Seeger, Werner ^{[19
,20
]}

Stevens, Molly M. ^{[21
,22
]}

Urban, Robert ^{[23
]}

Veldman, Alex ^{[24
,25
,26
]}

Wess, Guenther ^{[27
]}

Volk, Hans-Dieter ^{[1
,28
]}

机构：

[1] Charite, Berlin Brandenburg Ctr Regenerat Therapies, Berlin, Germany

[2] Charite, Julius Wolf Inst, Berlin, Germany

[3] Univ Utah, Dept Pharmaceut & Pharmaceut Chem Hlth Sci, Salt Lake City, UT 84112 USA

[4] AAAS, Washington, DC 20005 USA

[5] Univ Freiburg, Med Ctr, Dept Dermatol, D-79104 Freiburg, Germany

[6] German Res Fdn DFG, Bonn, Germany

[7] Univ Oxford, Nuffield Dept Orthopaed Rheumatol & Musculoskelet, Botnar Res Ctr, NIHR Biomed Res Unit, Oxford OX1 2JD, England

[8] Charite, Ctr Stroke Res, Berlin, Germany

[9] Charite, Dept Expt Neurol, Berlin, Germany

[10] Charite, Chairman Execut Board, D-10117 Berlin, Germany

[11] Baylor Coll Med, Houston Methodist Hosp, Texas Childrens Hosp, Ctr Cell & Gene Therapy, Houston, TX 77030 USA

[12] DePuy Synth Biomat, W Chester, PA 19380 USA

[13] Johannes Gutenberg Univ Mainz, Med Ctr, Translat Oncol TRON, Mainz, Germany

[14] Perelman Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA

[15] Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA

[16] Ctr Life Sci Boston Bldg, Wyss Inst, Boston, MA 02115 USA

[17] Berlin Inst Hlth, D-10117 Berlin, Germany

[18] Fed Minist Educ & Res, D-53175 Bonn, Germany

[19] UGMLC, Dept Pneumol, D-35392 Giessen, Germany

[20] German Ctr Lung Res DZL, D-35392 Giessen, Germany

[21] Univ London Imperial Coll Sci Technol & Med, Dept Mat, London SW7 2AZ, England

[22] Univ London Imperial Coll Sci Technol & Med, Inst Biomed Engn, Dept Bioengn, London SW7 2AZ, England

[23] J&J Boston Innovat Ctr, Cambridge, MA 02142 USA

[24] Monash Med Ctr, Monash Newborn, Melbourne, Vic 3168, Australia

[25] Inst Med Res, Monash Inst Med Res Prince Henrys Inst MIMR PHI, Ritchie Ctr, Melbourne, Vic 3168, Australia

[26] Monash Univ, Dept Paediat, Melbourne, Vic 3004, Australia

[27] German Res Ctr Environm Hlth, Helmholtz Zentrum Munchen, Munich, Germany

[28] Charite, Inst Med Immunol, Berlin, Germany

来源：

SCIENCE TRANSLATIONAL MEDICINE | 2014年 / 6卷 / 264期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会; 英国工程与自然科学研究理事会;

关键词：

CHALLENGES;

D O I：

10.1126/scitranslmed.aaa0599

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

Participants at the recent Translate! 2014 meeting in Berlin, Germany, reached a consensus on the rate-limiting factor for advancing translational medicine.

引用

页数：6

共 14 条

[1]

[Anonymous], 2013, NATURE, V496, P398

[2]

Fighting publication bias: introducing the Negative Results section [J].

Dirnagl, Ulrich ;

Lauritzen, Martin .

JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2010, 30 (07) :1263-1264

[3]

Revolution Stalled [J].

Hyman, Steven E. .

SCIENCE TRANSLATIONAL MEDICINE, 2012, 4 (155)

[4]

Playing Our Part [J].

Kelner, Katrina L. .

SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (190)

[5]

Mastering Translational Medicine: Interdisciplinary Education for a New Generation [J].

Kurpinski, Kyle ;

Johnson, Terry ;

Kumar, Sanjay ;

Desai, Tejal ;

Li, Song .

SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (218)

[6]

A call for transparent reporting to optimize the predictive value of preclinical research [J].

Landis, Story C. ;

Amara, Susan G. ;

Asadullah, Khusru ;

Austin, Chris P. ;

Blumenstein, Robi ;

Bradley, Eileen W. ;

Crystal, Ronald G. ;

Darnell, Robert B. ;

Ferrante, Robert J. ;

Fillit, Howard ;

Finkelstein, Robert ;

Fisher, Marc ;

Gendelman, Howard E. ;

Golub, Robert M. ;

Goudreau, John L. ;

Gross, Robert A. ;

Gubitz, Amelie K. ;

Hesterlee, Sharon E. ;

Howells, David W. ;

Huguenard, John ;

Kelner, Katrina ;

Koroshetz, Walter ;

Krainc, Dimitri ;

Lazic, Stanley E. ;

Levine, Michael S. ;

Macleod, Malcolm R. ;

McCall, John M. ;

Moxley, Richard T., III ;

Narasimhan, Kalyani ;

Noble, Linda J. ;

Perrin, Steve ;

Porter, John D. ;

Steward, Oswald ;

Unger, Ellis ;

Utz, Ursula ;

Silberberg, Shai D. .

NATURE, 2012, 490 (7419) :187-191

[7]

Mak IWY, 2014, AM J TRANSL RES, V6, P114

[8]

Reproducibility [J].

McNutt, Marcia .

SCIENCE, 2014, 343 (6168) :231-231

[9]

Culture of Impact: Faculty as Mentors for Student Entrepreneurs [J].

Prestwich, Glenn D. .

SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (169)

[10]

Central challenges facing the national clinical research enterprise [J].

Sung, NS ;

Crowley, WF ;

Genel, M ;

Salber, P ;

Sandy, L ;

Sherwood, LM ;

Johnson, SB ;

Catanese, V ;

Tilson, H ;

Getz, K ;

Larson, EL ;

Scheinberg, D ;

Reece, EA ;

Slavkin, H ;

Dobs, A ;

Grebb, J ;

Martinez, RA ;

Korn, A ;

Rimoin, D .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2003, 289 (10) :1278-1287

← 1 2 →