Spontaneous regression of renal cell carcinoma: a pitfall in diagnosis of renal lesions

被引:23
作者
Hamid, Y [1 ]
Poller, DN [1 ]
机构
[1] Queen Alexandra Hosp, Dept Histopathol, Portsmouth Acute Hosp NHS Trust, Portsmouth PO6 3LY, Hants, England
关键词
renal cell carcinoma; necrosis; regression;
D O I
10.1136/jcp.51.4.334
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Two cases of renal cell carcinoma, both of which underwent extensive spontaneous regression, are reported. The first occurred in a 56 year old man, forming a well circumscribed renal cortical nodule which contained only very occasional foci of viable renal cell carcinoma with areas of hyalinisation and calcification, and with metaplastic ossification. The second lesion was removed from an 82 year old man, comprising a cystic cavity containing necrotic debris with only occasional viable foci of classical renal cell carcinoma. Spontaneous regression of renal cell carcinoma is a rare but recognised entity. These two cases emphasise the important differential diagnoses: metastatic secondary carcinomas, xanthogranulomatous pyelonephritis, and infective granulomatous conditions of the kidney. The importance of adequate tissue sampling of all renal nodules cannot be overemphasised in the processing for examination of lesions within the kidney.
引用
收藏
页码:334 / 336
页数:3
相关论文
共 10 条
[1]  
BERNSTEIN J, 1987, AM J PATHOL, V129, P92
[2]   Spontaneous caval tumor thrombus necrosis and regression of pulmonary lesions in renal cell cancer [J].
Bos, SD ;
Mensink, HJA .
SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, 1996, 30 (06) :489-492
[3]   REGRESSION OF RENAL CELL HEPATIC METASTASIS FOLLOWING REMOVAL OF PRIMARY LESIONS [J].
DEWEERD, JH ;
HAWTHORNE, NJ ;
ADSON, MA .
JOURNAL OF UROLOGY, 1977, 117 (06) :790-792
[4]   XANTHOGRANULOMATOUS PYELONEPHRITIS (XGP) - LOCAL DISEASE WITH SYSTEMIC MANIFESTATIONS - REPORT OF 23 PATIENTS AND REVIEW OF THE LITERATURE [J].
GOODMAN, M ;
CURRY, T ;
RUSSELL, T .
MEDICINE, 1979, 58 (02) :171-181
[5]   RENAL EPITHELIAL HYPERPLASTIC AND NEOPLASTIC PROLIFERATION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY-DISEASE [J].
GREGOIRE, JR ;
TORRES, VE ;
HOLLEY, KE ;
FARROW, GM .
AMERICAN JOURNAL OF KIDNEY DISEASES, 1987, 9 (01) :27-38
[6]   RENAL-CELL CARCINOMA IN VON HIPPEL-LINDAU SYNDROME [J].
MALEK, RS ;
OMESS, PJ ;
BENSON, RC ;
ZINCKE, H .
AMERICAN JOURNAL OF MEDICINE, 1987, 82 (02) :236-238
[7]   REGRESSION OF METASTATIC RENAL-CELL CARCINOMA AFTER CYTOREDUCTIVE NEPHRECTOMY [J].
MARCUS, SG ;
CHOYKE, PL ;
REITER, R ;
JAFFE, GS ;
ALEXANDER, RB ;
LINEHAN, WM ;
ROSENBERG, SA ;
WALTHER, MM .
JOURNAL OF UROLOGY, 1993, 150 (02) :463-466
[8]  
MILLAN JC, 1989, UROPATHOLOGY, V2, P623
[9]   MULTILOCULAR CYSTIC RENAL-CELL CARCINOMA [J].
MURAD, T ;
KOMAIKO, W ;
OYASU, R ;
BAUER, K .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1991, 95 (05) :633-637
[10]  
Ordonez, 1996, ACKERMANS SURG PATHO, V1, P1059