Studies on the synthesis of elegan-type linear diterpenes: The efficient total syntheses of eleganolone, eleganolone acetate, elegandiol, eleganonal, and epoxyeleganolone

被引：13

作者：

Li, J

Lan, J

Liu, ZS

Li, YL ^{[1
]}

机构：

[1] Lanzhou Univ, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, Inst Organ Chem, Lanzhou 730000, Peoples R China

来源：

JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 01期

关键词：

D O I：

10.1021/np970227g

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The first total syntheses of five elegan-type linear diterpenes-eleganolone (1), eleganolone acetate (2), elegandiol (3), eleganonal (4), and epoxyeleganolone (5)-were accomplished starting from (E,E)-farnesol (6) via four to six steps, successively, with high overall yield. The key step was the alkylation reaction of silyl cyanide with allylic iodide.

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页码：92 / 95

页数：4

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