Biogenesis of the gram-negative bacterial outer membrane

被引:108
作者
Bos, MP
Tommassen, J
机构
[1] Univ Utrecht, Dept Mol Microbiol, NL-3584 CH Utrecht, Netherlands
[2] Univ Utrecht, Inst Biomembranes, NL-3584 CH Utrecht, Netherlands
关键词
D O I
10.1016/j.mib.2004.10.011
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Gram-negative bacteria are bounded by two membranes. The outer membrane consists of phospholipids, lipopolysaccharides, lipoproteins and integral outer membrane proteins, all of which are synthesized in the cytoplasm. Recently, much progress has been made in the elucidation of the mechanisms of transport of these molecules over the inner membrane, through the periplasm and into the outer membrane, in part by exploiting the extraordinary capacity of Neisseria meningritidis to survive without lipopolysaccharide.
引用
收藏
页码:610 / 616
页数:7
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