The importance and features of the distal airways in children and adults

被引:42
作者
Gelfand, Erwin W. [1 ]
Kraft, Monica [2 ]
机构
[1] Natl Jewish Hlth, Dept Pediat, Denver, CO USA
[2] Duke Univ, Dept Med, Durham, NC 27706 USA
关键词
Asthma; small airways; distal airways; adult; children; clinical; therapeutic; LUNG-FUNCTION; INHALED CORTICOSTEROIDS; CHILDHOOD ASTHMA; ALVEOLAR TISSUE; INFLAMMATION; OBSTRUCTION; SYMPTOMS; LIFE; SENSITIZATION; SEVERITY;
D O I
10.1016/j.jaci.2009.07.062
中图分类号
R392 [医学免疫学];
学科分类号
100108 [医学免疫学];
摘要
Asthma remains a major problem worldwide, even with new categories of medications that have been brought into the therapeutic armamentarium. One area of disease pathology and physiology that is involved in the pathobiology of asthma is the distal (small) airways. Better understanding of this area in both the pediatric and adult asthmatic populations will lead to improved targeted therapy for all asthmatic patients. This article discusses the importance of the distal airways for both children and adults with asthma. (J Allergy Clin Immunol 2009;124:S84-7.)
引用
收藏
页码:S84 / S87
页数:4
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