The question of exactly how science is commercialized is an important one. While the social structures of "science" and "technology" are distinctive, recent work suggests that scientific and technological ideas in fact co-evolve. This paper addresses the dynamics of such co-evolution: are scientific networks deeply co-mingled with networks through which technology is created and if so how? It does so in a study of an emerging area of biomedicine-tissue engineering. The research is based on a novel methodology that takes advantage of the fact that an idea is often inscribed in both a patent and paper, thus forming a patent-paper pair. Starting with the pair, it is possible to trace the citation network of patents, papers, inventors and authors, combining traditional bibliometric analysis with in-depth interviews to provide new insights. The results show that for this case there exist distinctive scientific and technological networks. Furthermore, while there is evidence of overlap, it is neither co-publishing nor citation as might be predicted from current literature. Rather co-mingling exists through founding, licensing, consulting and advising. This has implications for our understanding of the processes through which spillovers arise, the way in which commercialization and technology transfer should be structured and for recent debates on conflict of interest in biomedicine. (C) 2002 Elsevier Science B.V. All rights reserved.
