Two sets of Staphylococcus aureus isolates recovered from two patients exhibited similar susceptibility profiles except for oxacillin susceptibility (MSSA) or resistance (MRSA). SmaI macrorestriction and inter-IS256 PCR analysis showed patterns closely related to the Belgian epidemic MRSA clone 1 in each pair of MSSA/MRSA strains. Loss of one large SmaI DNA fragment and concurrent gain of a smaller fragment in the MSSA isolates was observed. The mecA sequence present in the MRSA was absent in the MSSA variant. Therefore, in vivo deletion of the mec region may occur in some lineages of S. aureus more frequently than previously thought.
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AUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIAAUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIA
INGLIS, B
ELADHAMI, W
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AUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIAAUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIA
ELADHAMI, W
STEWART, PR
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AUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIAAUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIA
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AUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIAAUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIA
INGLIS, B
ELADHAMI, W
论文数: 0引用数: 0
h-index: 0
机构:
AUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIAAUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIA
ELADHAMI, W
STEWART, PR
论文数: 0引用数: 0
h-index: 0
机构:
AUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIAAUSTRALIAN NATL UNIV, FAC SCI, DIV BIOCHEM & MOLEC BIOL, CANBERRA, ACT 2601, AUSTRALIA