Control of heat produced during ATP hydrolysis by the sarcoplasmic reticulum Ca2+-ATPase in the absence of a Ca2+ gradient

被引：15

作者：

de Meis, L ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro, Dept Bioquim Med, Inst Ciencias Biomed, BR-21941590 Rio De Janeiro, Brazil

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1998年 / 243卷 / 02期

关键词：

D O I：

10.1006/bbrc.1997.8028

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The amount of heat produced during the hydrolysis of ATP by the sarcoplasmic reticulum Ca2+-ATPase was found to vary depending on the Ca2+ concentrtion in the medium. When the CaCl2 concentration is raised from 0.1 to 2.0 mM a part of the energy derived from ATP hydrolysis is not dissipated as heat but it is used by the enzyme to resinthesize a small fraction of the ATP previously cleaved. Thus, Ca2+ seems to regulate the ATPase in such a way as to vary the fraction of energy derived from ATP hydrolysis which is converted into heat and that which is conserved as chemical energy. (C) 1998 Academic Press.

引用

页码：598 / 600

页数：3

共 26 条

[1] ACTIVATION OF CALCIUM EFFLUX BY ADP AND INORGANIC PHOSPHATE [J].