Activin and bone morphogenetic protein (BMP) signalling during tooth development

被引：16

作者：

Heikinheimo, K ^{[1
]}

Begue-Kirn, C

Ritvos, O

Tuuri, T

Ruch, JV

机构：

[1] Univ Turku, Inst Dent, FIN-20520 Turku 52, Finland

[2] Univ Helsinki, Haartman Inst, Dept Pathol, Helsinki, Finland

[3] Univ Helsinki, Haartman Inst, Dept Bacteriol, Helsinki, Finland

[4] Univ Strasbourg 1, Inst Med Biol, Fac Med, Strasbourg, France

来源：

EUROPEAN JOURNAL OF ORAL SCIENCES | 1998年 / 106卷

关键词：

activin A; BMPs; follistatin; odontogenesis; TGF-beta receptors;

D O I：

10.1111/j.1600-0722.1998.tb02171.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Activins and bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related cytokines. Results of recent in vivo and in vitro studies suggest that activin A, several BMPs, and their cell surface receptors may participate in tooth development. In addition, follistatin, an extracellular protein that may interact with activin and BMP signaling, appears to be involved. This review focuses on recent advances In relation to the roles of activin/BMP receptors, their ligands and extracellular modifiers during tooth development.

引用

页码：167 / 173

页数：7

共 60 条

[1]

Attisano L, 1996, MOL CELL BIOL, V16, P1066

[2] NOVEL ACTIVIN RECEPTORS - DISTINCT GENES AND ALTERNATIVE MESSENGER-RNA SPLICING GENERATE A REPERTOIRE OF SERINE THREONINE KINASE RECEPTORS [J].