Persistent neural activity: prevalence and mechanisms

被引：236

作者：

Major, G ^{[1
]}

Tank, D

机构：

[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA

[2] Princeton Univ, Dept Phys, Princeton, NJ 08544 USA

来源：

CURRENT OPINION IN NEUROBIOLOGY | 2004年 / 14卷 / 06期

关键词：

D O I：

10.1016/j.conb.2004.10.017

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Persistent neural activity refers to a sustained change in action potential discharge that long outlasts a stimulus. It is found in a diverse set of brain regions and organisms and several in vitro systems, suggesting that it can be considered a universal form of circuit dynamics that can be used as a mechanism for short-term storage and accumulation of sensory or motor information. Both single cell and network mechanisms are likely to co-operate in generating persistent activity in many brain areas.

引用

收藏

页码：675 / 684

页数：10

相关论文

共 79 条

[1] Anatomy and discharge properties of pre-motor neurons in the goldfish medulla that have eye-position signals during fixations [J].

Aksay, E ;

Baker, R ;

Seung, HS ;

Tank, DW .

JOURNAL OF NEUROPHYSIOLOGY, 2000, 84 (02) :1035-1049

[2]

Aksay E, 2003, J NEUROSCI, V23, P10852

[3] History dependence of rate covariation between neurons during persistent activity in an oculomotor integrator [J].

Aksay, E ;

Major, G ;

Goldman, MS ;

Baker, R ;

Seung, HS ;

Tank, DW .

CEREBRAL CORTEX, 2003, 13 (11) :1173-1184

[4] In vivo intracellular recording and perturbation of persistent activity in a neural integrator [J].

Aksay, E ;

Gamkrelidze, G ;

Seung, HS ;

Baker, R ;

Tank, DW .

NATURE NEUROSCIENCE, 2001, 4 (02) :184-193

[5]

AKSAY E, 2001, SOC NEUR ABSTR, V31

[6]

Alaburda A, 2002, ADV EXP MED BIOL, V508, P219

[7] EFFECTS OF COOLING PREFRONTAL CORTEX ON CELL FIRING IN NUCLEUS MEDIALIS DORSALIS [J].

ALEXANDER, GE ;

FUSTER, JM .

BRAIN RESEARCH, 1973, 61 (OCT26) :93-105

[8] Dynamics of population code for working memory in the prefrontal cortex [J].

Baeg, EH ;

Kim, YB ;

Huh, K ;

Mook-Jung, I ;

Kim, HT ;

Jung, MW .

NEURON, 2003, 40 (01) :177-188

[9] Timing and neural encoding of somatosensory parametric working memory in macaque prefrontal cortex [J].

Brody, CD ;

Hernández, A ;

Zainos, A ;

Romo, R .

CEREBRAL CORTEX, 2003, 13 (11) :1196-1207

[10] Basic mechanisms for graded persistent activity: discrete attractors, continuous attractors, and dynamic representations [J].

Brody, CD ;

Romo, R ;

Kepecs, A .

CURRENT OPINION IN NEUROBIOLOGY, 2003, 13 (02) :204-211

← 1 2 3 4 5 6 7 8 →