A bifunctional approach towards the mild oxidation of organic halides:: 2-dimethylamino-N,N-dimethylaniline N-oxide

被引：40

作者：

Chandrasekhar, S ^{[1
]}

Sridhar, M ^{[1
]}

机构：

[1] Indian Inst Sci, Dept Organ Chem, Bangalore 560012, Karnataka, India

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 28期

关键词：

D O I：

10.1016/S0040-4039(00)00874-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The titled reagent incorporates an oxygen-centred nucleophile and a basic moiety-in a suitably mutual orientation-in the same molecule. It oxidises various primary benzylic bromides to the corresponding aromatic aldehydes under relatively mild conditions (MeCN/rt-50 degrees C/6-24 h) in high yields (83-97%), and is thus a useful alternative to the Kornblum procedure. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：5423 / 5425

页数：3