Reagentless detection of microorganisms by intrinsic fluorescence

被引:51
作者
Estes, C [1 ]
Duncan, A [1 ]
Wade, B [1 ]
Lloyd, C [1 ]
Ellis, W [1 ]
Powers, L [1 ]
机构
[1] Utah State Univ, Dept Elect Engn, Natl Ctr Design Mol Funct, Logan, UT 84322 USA
关键词
microbe sensor; intrinsic fluorescence; optical detection; microbial contamination;
D O I
10.1016/S0956-5663(03)00008-3
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Quick and accurate detection of microbial contamination is accomplished by a unique combination of leading-edge technologies described in this and the accompanying paper. In this contribution, a hand-held prototype instrument is described which is capable of statistically sampling the environment for microbial contamination and determining cell viability. The technology is sensitive enough to detect very low levels (similar to20 cells/cm(2) or cm(3)) of microbes in seconds. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:511 / 519
页数:9
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