Usefulness of staging laparoscopy for advanced gastric cancer

被引:26
作者
Shimizu, Hiroki [1 ]
Imamura, Hiroshi [2 ]
Ohta, Katsuya [2 ]
Miyazaki, Yasuhiro
Kishimoto, Tomono [2 ]
Fukunaga, Mutsumi [2 ]
Ohzato, Hiroki [2 ]
Tatsuta, Masayuki [2 ]
Furukawa, Hiroshi [2 ]
机构
[1] Japanese Red Cross Kyoto Daiichi Hosp, Dept Surg, Higashiyama Ku, Kyoto 6050981, Japan
[2] Sakai Municipal Hosp, Dept Surg, Osaka, Japan
关键词
Advanced gastric cancer; Staging laparoscopy; Peritoneal cytology; Neoadjuvant chemotherapy; Surgery; PROGNOSTIC VALUE; CYTOLOGY; MANAGEMENT; CARCINOMA; CISPLATIN;
D O I
10.1007/s00595-009-4017-6
中图分类号
R61 [外科手术学];
学科分类号
摘要
The aim of this study was to clarify the usefulness of staging laparoscopy for planning the treatment strategy in patients with advanced gastric cancer. This was a retrospective study of patients with gastric cancer who underwent staging laparoscopy. The patients were divided into three groups according to the presence/absence of peritoneal metastasis (P) and positive peritoneal cytology (CY): P negative (0) CY0, P0CY positive (1), and P1CY1. The treatment strategy after staging laparoscopy was as follows: (1) surgery for the P0CY0 group, (2) surgery with neoadjuvant chemotherapy (NAC) for the P0CY1 group, and (3) chemotherapy for the P1CY1 group. Survival was estimated by the Kaplan-Meier method and statistical differences were analyzed by the log-rank test. Thirty-four patients were included in this study: 11 in the P0CY0 group, 13 in the P0CY1 group, and 10 in the P1CY1 group. A gastrectomy was done in 11, 10, and no patients, respectively. The survival rate of the P0CY0 patients was significantly better than that of the P0CY1 or P1CY1 patients (P = 0.0106 and 0.0031, respectively). Staging laparoscopy is useful for planning the treatment strategy and estimating the prognosis of patients with advanced gastric cancer.
引用
收藏
页码:119 / 124
页数:6
相关论文
共 19 条
[1]   Laparoscopy significantly improves the perceived preoperative stage of gastric cancer [J].
Guy R.J.C. Blackshaw ;
Jonathan D. Barry ;
Paul Edwards ;
Miles C. Allison ;
Gerald V. Thomas ;
Wyn G. Lewis .
Gastric Cancer, 2003, 6 (4) :225-229
[2]   Prognostic value of positive cytology findings from abdominal washings in patients with gastric cancer [J].
Bonenkamp, JJ ;
Songun, I ;
Hermans, J ;
vandeVelde, CJH ;
vanElk, P ;
Gouma, DJ ;
Obertop, H ;
Taat, CW ;
Meyer, S ;
Plukker, J ;
Tilanus, H ;
Welvaart, K ;
Sasako, M ;
Fleuren, GJ ;
Bruijn, JA ;
Arends, JW ;
Grond, ALN ;
vandeStadt, J .
BRITISH JOURNAL OF SURGERY, 1996, 83 (05) :672-674
[3]   Laparoscopy in the management of gastric adenocarcinoma [J].
Burke, EC ;
Karpeh, MS ;
Conlon, KC ;
Brennan, MF .
ANNALS OF SURGERY, 1997, 225 (03) :262-267
[4]   Selection of locally advanced gastric carcinoma by preoperative staging laparoscopy [J].
DUgo, DM ;
Persiani, R ;
Caracciolo, F ;
Ronconi, P ;
Coco, C ;
Picciocchi, A .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 1997, 11 (12) :1159-1162
[5]   Neoadjuvant chemotherapy with P-ELF (cisplatin, etoposide, leucovorin, 5-fluorouracil) followed by radical resection in patients with initially unresectable gastric adenocarcinoma:: A phase II study [J].
Gallardo-Rincón, D ;
Oñate-Ocaña, LF ;
Calderillo-Ruiz, G .
ANNALS OF SURGICAL ONCOLOGY, 2000, 7 (01) :45-50
[6]   Recent results of therapy for scirrhous gastric cancer [J].
Ikeguchi, Masahide ;
Miyake, Takanori ;
Matsunaga, Tomoyuki ;
Yamamoto, Manabu ;
Fukumoto, Youji ;
Yamada, Yosinori ;
Fukuda, Kenji ;
Saito, Hiroaki ;
Tatebe, Shigeru ;
Tsujitani, Shun-ichi .
SURGERY TODAY, 2009, 39 (04) :290-294
[7]  
Japanese Gastric Cancer Association, 1998, Gastric Cancer, V1, P10
[8]  
Kodera Y, 1999, J SURG ONCOL, V72, P60, DOI 10.1002/(SICI)1096-9098(199910)72:2<60::AID-JSO3>3.0.CO
[9]  
2-1
[10]   S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III trial [J].
Koizumi, Wasaburo ;
Narahara, Hiroyuki ;
Hara, Takuo ;
Takagane, Akinori ;
Akiya, Toshikazu ;
Takagi, Masakazu ;
Miyashita, Kosei ;
Nishizaki, Takashi ;
Kobayashi, Osamu ;
Takiyama, Wataru ;
Toh, Yasushi ;
Nagaie, Takashi ;
Takagi, Seiichi ;
Yamamura, Yoshitaka ;
Yanaoka, Kimihiko ;
Orita, Hiroyuki ;
Takeuchi, Masahiro .
LANCET ONCOLOGY, 2008, 9 (03) :215-221