Duration of viraemia and faecal viral excretion in acute hepatitis E

被引：121

作者：

Aggarwal, R ^{[1
]}

Kini, D

Sofat, S

Naik, SR

Krawczynski, K

机构：

[1] Sanjay Gandhi Postgrad Inst Med Sci, Dept Gastroenterol, Lucknow 226014, Uttar Pradesh, India

[2] Ctr Dis Control & Prevent, Hepatitis Branch, DVRD NCID, Atlanta, GA 30333 USA

[3] Base Hosp, Lucknow, Uttar Pradesh, India

来源：

LANCET | 2000年 / 356卷 / 9235期

关键词：

D O I：

10.1016/S0140-6736(00)02737-9

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Data on duration of viral excretion and viraemia during hepatitis E virus (HEV) infection are limited. We tested serial stool and serum samples from 20 patients with acute hepatitis E for HEV RNA. Faecal excretion and viraemia in these patients were found to be short lived. In 19 patients, all samples obtained after biochemical resolution of hepatitis tested negative; in the remaining patient, HEV RNA was detected in the serum samples but not in stool after biochemical resolution. Long-term persistence of HEV in body fluids of infected individuals seems to be an unlikely reservoir for transmission of HEV.

引用

页码：1081 / 1082

页数：2

共 5 条

[1] Hepatitis E virus RNA detection in serum and feces specimens with the use of microspin columns [J].

Aggarwal, R ;

McCaustland, KA .

JOURNAL OF VIROLOGICAL METHODS, 1998, 74 (02) :209-213

[2] HEPATITIS-E VIRUS TRANSMISSION TO A VOLUNTEER [J].

CHAUHAN, A ;

JAMEEL, S ;

DILAWARI, JB ;

CHAWLA, YK ;

KAUR, U ;

GANGULY, NK .

LANCET, 1993, 341 (8838) :149-150

[3] VIREMIA, FECAL SHEDDING, AND IGM AND IGG RESPONSES IN PATIENTS WITH HEPATITIS-E [J].

CLAYSON, ET ;

MYINT, KSA ;

SNITBHAN, R ;

VAUGHN, DW ;

INNIS, BL ;

CHAN, L ;

CHEUNG, P ;

SHRESTHA, MP .

JOURNAL OF INFECTIOUS DISEASES, 1995, 172 (04) :927-933

[4] PROTRACTED VIREMIA DURING ACUTE SPORADIC HEPATITIS-E VIRUS-INFECTION [J].

NANDA, SK ;

ANSARI, IH ;

ACHARYA, SK ;

JAMEEL, S ;

PANDA, SK .

GASTROENTEROLOGY, 1995, 108 (01) :225-230

[5] VIREMIA IN EGYPTIAN CHILDREN WITH HEPATITIS-E VIRUS-INFECTION [J].

SCHLAUDER, GG ;

DAWSON, GJ ;

MUSHAHWAR, IK ;

RITTER, A ;

SUTHERLAND, R ;

MOANESS, A ;

KAMEL, MA .

LANCET, 1993, 341 (8841) :378-378

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