Behavioural measures in frontotemporal lobar dementia and other dementias: The utility of the frontal behavioural inventory and the neuropsychiatric inventory in a national cohort study

被引:26
作者
Blair, M. [1 ]
Kertesz, A.
Davis-Faroque, N.
Hsiung, G.-Y. R.
Black, S. E.
Bouchard, R. W.
Gauthier, S.
Guzman, D. A.
Hogan, D. B.
Rockwood, K.
Feldman, H.
机构
[1] Univ Western Ontario, St Josephs Hlth Care, Dept Cognit Neurol, London, ON N6A 4V2, Canada
[2] Univ Western Ontario, St Josephs Hlth Care, Alzheimers Res Ctr, London, ON N6A 4V2, Canada
[3] Univ British Columbia, Dept Med Neurol, Vancouver, BC V5Z 1M9, Canada
[4] Univ Toronto, Dept Med Neurol, Toronto, ON, Canada
[5] Univ Laval, Dept Med Neurol, Quebec City, PQ, Canada
[6] McGill Univ, McGill Ctr Studies Aging, Montreal, PQ, Canada
[7] Univ Ottawa, Dept Med Neurol, Ottawa, ON, Canada
[8] Univ Calgary, Dept Med Geriatr Med, Calgary, AB, Canada
[9] Dalhousie Univ, Dept Med Geriatr Med Neurol, Halifax, NS, Canada
关键词
frontotemporal lobar dementia; frontotemporal dementia; Pick's disease; Pick complex; Alzheimer's disease; Alzheimer's type dementia; frontal behavioural inventory; neuropsychiatric inventory; Canadian Collaborative Cohort of Related Dementias;
D O I
10.1159/000101908
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: Distinguishing between patients with frontotemporal lobar dementia (FTLD) and other dementing illnesses remains a difficult task for many clinicians. In this study, we aimed to provide further evidence for the construct validity of the frontal behavioural inventory ( FBI) and assess its utility in differentiating FTLD patients from other groups using data from the Canadian Collaborative Cohort of Related Dementias ( ACCORD) study. Method: Baseline scores on the FBI and neuropsychiatric inventory (NPI) were compared among several clinical groups (n = 177). Results: The FBI discriminated a higher percentage of FTLD patients ( > 75% correct classification) from Alzheimer's disease and other groups compared to the NPI (54.2%). Conclusion: This study provides good evidence for convergent validity between the FBI and NPI (r = 0.72), indicating that both measures capture similar psychopathology in this nationwide cohort. Copyright (c) 2007 S. Karger AG, Basel.
引用
收藏
页码:406 / 415
页数:10
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