Biomacromolecule surface recognition using nanoparticles

被引：11

作者：

Goodman, CM ^{[1
]}

Rotello, VM ^{[1
]}

机构：

[1] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

来源：

MINI-REVIEWS IN ORGANIC CHEMISTRY | 2004年 / 1卷 / 01期

基金：

美国国家卫生研究院;

关键词：

noncovalent interactions; nanoparticle; monolayer-protected clusters; biomolecular recognition;

D O I：

10.2174/1570193043488935

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Mono layer-protected nanoparticles represent a new class of receptors, capable of high affinity, multivalent binding with biomolecules. Networks of self-optimizing bioactive substituents can be introduced via facile place-exchange of functionalized thiols, approximating the diversified topology of biological surfaces. Extension of these particles to model systems and in catalysis is described.

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收藏

页码：103 / 114

页数：12

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