Screening for Staphylococcus aureus with a reduced susceptibility to vancomycin in:: a Belgian hospital

被引:6
作者
Piérard, D [1 ]
Vandenbussche, H [1 ]
Verschraegen, I [1 ]
Lauwers, S [1 ]
机构
[1] Free Univ Brussels, Acad Ziekenhuis, Dept Microbiol, B-1090 Brussels, Belgium
来源
PATHOLOGIE BIOLOGIE | 2004年 / 52卷 / 08期
关键词
VISA; Staphylococcus aureus; glycopeptides; vancomycin; MRSA;
D O I
10.1016/j.patbio.2004.07.016
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The aim of the present study was to investigate the prevalence of vancomycin resistance in clinical methicillin resistant Staphylococcus aureus (MRSA) isolates in our hospital by screening on Mueller-Hinton agar with 5 mg/l teicoplanin (MH-Teico), as recommended by the Comite de l'Antibiogramme of the Societe Franqaise de Microbiologie (CA-SFM). Seventeen of 1002 clinical MRSA isolated from 404 patients showed in 2003 growth of at least four colonies on this medium, but only one was confirmed as homogeneous vancomycin-resistant S. aureus (VISA) and five as heterogeneous VISA (hVISA) by population analysis. None of the patients presented with severe infection but awareness is needed and screening on MH-Teico as recommended by CA-SFM is a convenient method. Surveillance should be focused on patients with risk factors for selection of such strains: patients with a prolonged course of glycopeptide therapy and persistence of MRSA infection or colonization. (C) 2004 Elsevier SAS. All rights reserved.
引用
收藏
页码:486 / 488
页数:3
相关论文
共 7 条
[1]   Emergence of vancomycin-intermediate Staphylococcus aureus in a Belgian hospital:: microbiological and clinical features [J].
Denis, O ;
Nonhoff, C ;
Byl, B ;
Knoop, C ;
Bobin-Dubreux, S ;
Struelens, MJ .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 50 (03) :383-391
[2]  
Gemmell Curtis G., 2004, Journal of Infection and Chemotherapy, V10, P69, DOI 10.1007/s10156-004-0307-5
[3]   Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin [J].
Hiramatsu, K ;
Aritaka, N ;
Hanaki, H ;
Kawasaki, S ;
Hosoda, Y ;
Hori, S ;
Fukuchi, Y ;
Kobayashi, I .
LANCET, 1997, 350 (9092) :1670-1673
[4]  
*NAT I PUBL HLTH E, 2003, EARSS ANN REP 2002
[5]  
*SOC FRANC MICR, 2004, COMM 2004
[6]   Evaluation of current methods for detection of staphylococci with reduced susceptibility to glycopeptides [J].
Walsh, TR ;
Bolmström, A ;
Qwärnström, A ;
Ho, P ;
Wootton, M ;
Howe, RA ;
MacGowan, AP ;
Diekema, D .
JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (07) :2439-2444
[7]  
2004, MMWR, V53, P322