Cochinolide, a new γ-alkylidene bicyclic butenolide with antiviral activity, and its β-glucopyranoside from Homalium cochinchinensis

被引：36

作者：

Ishikawa, T

Nishigaya, K

Uchikoshi, H

Chen, IS

机构：

[1] Chiba Univ, Fac Pharmaceut Sci, Chiba 2638522, Japan

[2] Kaohsiung Med Coll, Grad Inst Nat Prod, Kaohsiung 807, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 04期

关键词：

D O I：

10.1021/np970341z

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new gamma-alkylidene bicyclic butenolide designated as cochinolide (1) and its beta-glucopypanoside (3) were isolated from the root bark of Homalium cochinchinensis (Flacoutiaceae). Their structures, except absolute stereochemistries, were determined by spectroscopic means. Cochinolide (1) showed moderate antiviral activities against HSV-1 and -2.

引用

页码：534 / 537

页数：4

共 7 条

[1]

Chansakaow S, 1996, CHEM PHARM BULL, V44, P1415, DOI 10.1248/cpb.44.1415

[2]

GAN WS, 1965, MANUAL MED PLANTS TA, V3, P567

[3] A BUTENOLIDE ATYPICAL OF THE RANUNCULACEAE - AQUILEGIOLIDE FROM AQUILEGIA-ATRATA (VAR ATROVIOLACEA) [J].