A novel molecular system for nitric oxide detection with high sensitivity

被引：15

作者：

Katayama, Y ^{[1
]}

Soh, N ^{[1
]}

Koide, K ^{[1
]}

Maeda, M ^{[1
]}

机构：

[1] Kyushu Univ, Fac Engn, Dept Appl Chem, Higashi Ku, Fukuoka 8128581, Japan

来源：

CHEMISTRY LETTERS | 2000年 / 10期

关键词：

D O I：

10.1246/cl.2000.1152

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel molecular switching system was developed for the direct detection of endogenous nitric oxide. The system is comprised from an Fe(II)-dithiocarbamate complex in which TEMPOL molecule coordinates to the centered iron through a redox interaction. Nitric oxide binds to the iron to liberate the TEMPOL. The system will be potentially useful for the monitoring of endogenous nitric oxide.

引用

页码：1152 / 1153

页数：2

共 12 条

[1]

Akaike T, 1996, METHOD ENZYMOL, V268, P211

[2] MEASUREMENT OF NITRIC-OXIDE IN BIOLOGICAL MODELS [J].

ARCHER, S .

FASEB JOURNAL, 1993, 7 (02) :349-360

[3] TRIS(DITHIOCARBAMATO) COMPLEXES OF IRON(II), IRON(III), AND IRON(IV) - ELECTROCHEMICAL STUDY [J].

CHANT, R ;

HENDRICKSON, AR ;

MARTIN, RL ;

ROHDE, NM .

INORGANIC CHEMISTRY, 1975, 14 (08) :1894-1902

[4]

Estévez AG, 1998, PROG BRAIN RES, V118, P269

[5]

Gurlo T, 1999, J IMMUNOL, V163, P5770

[6] DETECTION OF NITRIC-OXIDE PRODUCTION IN LIPOPOLYSACCHARIDE-TREATED RATS BY ESR USING CARBON-MONOXIDE HEMOGLOBIN [J].

KOSAKA, H ;

WATANABE, M ;

YOSHIHARA, H ;

HARADA, N ;

SHIGA, T .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 184 (02) :1119-1124

[7] A REDOX-BASED MECHANISM FOR THE NEUROPROTECTIVE AND NEURODESTRUCTIVE EFFECTS OF NITRIC-OXIDE AND RELATED NITROSO-COMPOUNDS [J].

LIPTON, SA ;

CHOI, YB ;

PAN, ZH ;

LEI, SZZ ;

CHEN, HSV ;

SUCHER, NJ ;

LOSCALZO, J ;

SINGEL, DJ ;

STAMLER, JS .

NATURE, 1993, 364 (6438) :626-632

[8] Endogenous renal nitric oxide metabolism following experimental infrarenal aortic cross-clamp-induced ischaemia-reperfusion injury [J].

Pararajasingam, R ;

Weight, SC ;

Bell, PRF ;

Nicholson, ML ;

Sayers, RD .

BRITISH JOURNAL OF SURGERY, 1999, 86 (06) :795-799

[9] NITRIC-OXIDE - BIOLOGICAL MEDIATOR, MODULATOR AND EFFECTOR [J].

RADOMSKI, MW .

ANNALS OF MEDICINE, 1995, 27 (03) :321-329

[10] Spectral and kinetic studies on the activation of soluble guanylate cyclase by nitric oxide [J].

Stone, JR ;

Marletta, MA .

BIOCHEMISTRY, 1996, 35 (04) :1093-1099

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