A new cine-substitution of alkenyl Sulfones with aryltitanium reagents catalyzed by rhodium: Mechanistic studies and catalytic asymmetric synthesis of allylarenes

被引：65

作者：

Yoshida, K ^{[1
]}

Hayashi, T ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Kyoto 6068502, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2003年 / 125卷 / 10期

关键词：

D O I：

10.1021/ja0295568

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of alkenyl sulfones with aryltitanium triisopropoxide (ArTi(OPr-i )3) in the presence of 3 mol % of [Rh(OH)((S)-binap)]2 in THF at 40 °C gave high yield of cine-substitution products. The catalytic cycle was established by deuterium-labeling studies, and it was applied to catalytic asymmetric synthesis of allylarenes which proceeds with over 99% enantioselectivity. Copyright © 2003 American Chemical Society.

引用

页码：2872 / 2873

页数：2

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