The 1D blind deconvolution algorithm using maximum time delay slice of the third-order moment ((MTDS-TOM)[Lu, W]) is extended to 2D blind deconvolution for spotted image deblurring. A scaled and shifted version of the image is obtained using a special slice selected from its third-order moment, which is estimated using a 4D blind deconvolution. An application of the proposed method for removing the optical blur of a microarray image is given.